WebMar 1, 2024 · Furthermore, behavioral abnormalities and cerebellar neuropathologies observed in MIA control offspring are prevented in Cyp19-Cre +;Il6ra fl/fl offspring. Our results demonstrate that IL-6 activation in placenta is required for relaying inflammatory signals to the fetal brain and impacting behaviors and neuropathologies relevant to ... WebMar 7, 2024 · Tg (CYP19A1-cre)1Jri Transgene Detail Summary Transgene origin Transgene description Recombinase activity Phenotypes Disease models Tumor …
Expression of Cre recombinase in early diploid trophoblast cells of …
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Conditional Gene Deletion in the Placenta Using the Cre …
WebAug 22, 2024 · Decreased implantation areas in YB-1 fl/fl-mated Cyp19-Cre females compared to YB-1 fl/fl-mated WT females from GD8 onwards. (A) Implantation areas of single implantations of Cyp19-Cre x YB-1 fl/fl (n = 6–16) or WT x YB-1 fl/fl (n = 6–18) matings at GD5, 8, 10 and 12. Results are presented as means showing individual … WebAug 31, 2024 · Conditional depletion of Nrg1 in ovarian granulosa cells (Kawashima et al., 2014) was achieved by crossing Cyp19-Cre mice (Fan et al., 2008) with Nrg1 flox/flox mice (Yang et al., ... (Nrg1 flox/flox, WT and … WebJun 5, 2024 · Moreover, as expected, normal labyrinth formation was observed in DNMAMLf/+ / Cyp19cre/+ placenta, in which DNMAML functions specifically in trophoblast cells (Fig. 5c ), consistent with the... grasshopper call system