WebThe recommended dose of Dupilumab for adult patients is as follows: • Initial dose of 600 mg by subcutaneous injection (two 300 mg injections consecutively in different injection sites), followed by 300 mg given every other week. If a dose is missed, administer the dose as soon as possible. Thereafter, resume dosing at the regular scheduled time. Web24 set 2024 · Dupilumab è indicato per il trattamento a lungo termine. Il bisogno di proseguire la terapia dovrebbe essere riconsiderato almeno annualmente, sulla base della valutazione del livello di controllo dell’asma nel paziente, condotta dal medico. Rinosinusite cronica con poliposi nasale (CRSwNP)
Thông tin thuốc của Dupilumab MIMS Vietnam - Drug
Web12 mar 2024 · Dupilumab, a human monoclonal antibody against interleukin-4 receptor alpha, has demonstrated efficacy and an acceptable safety profile in adult and pediatric … WebFunctional dupilumab exposure was similar for dupilumab administered at both fast and slow injection rates, and the results were consistent with those observed in the studies described above. The mean values with fast versus slow dupilumab injection rates were 34.4 mg/L versus 35.0 mg/L, respectively, for C max and 630 day·mg/L versus 530 … bnf 77
Dupilumab-associated ocular surface disease: presentation, management ...
Web20 ott 2016 · Summary. Dupilumab is a monoclonal antibody used to treat moderate to severe atopic dermatitis, asthma, and nasal polyps accompanied by chronic … Web10 feb 2024 · Dupilumab is a human monoclonal IgG4 antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13) signaling by binding to the IL-4Rα subunit. Blocking IL … Web12 mar 2024 · Following dupilumab 200-mg SC injection, dupilumab exposure in serum was similar for both AI and PFS-S. The geometric mean ratios of PK parameters with 90% confidence intervals were 1.08 (0.97-1.21) for maximum serum concentration (C max ) and 1.11 (0.96-1.28) for area under the serum concentration–time curve until the last … clicks free delivery