WebMar 27, 2024 · Introduction. Cytoplasmic dynein 1 (dynein) is a microtubule (MT) motor protein complex that is responsible for retrograde transport of cellular cargos such as proteins, RNAs, and organelles 1, 2.Dynein is composed of four subunit classes: the heavy chain (HC), light intermediate chain (LIC), intermediate chain (IC), and light chain … WebJun 1, 2002 · Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles (PubMed:29742051). …
Q9P225 - UniProt
WebAbstract. Dynein is the large molecular motor that translocates to the (-) ends of microtubules. Dynein was first isolated from Tetrahymena cilia four decades ago. The analysis of the primary structure of the dynein heavy chain and the discovery that many organisms express multiple dynein heavy chains have led to two insights. WebDynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.. Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes.Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides.TCTEX1 is a … downtown excelsior minnesota
UniProt
WebEach light chain family has at least 2 members. Table II. ... The second type of cytoplasmic dynein, cytoplasmic dynein 2, is responsible for a component of intraflagellar transport (IFT), specifically the transport of protein complexes from the tips of cilia and flagella to their base, that occurs between the axonemal microtubules and the ... Dyneins are a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical work. Dynein transports various cellular cargos, provides forces and displacements important in mitosis, and drives the beat of eukaryotic cilia and flagella. All of these functions rely on dynein's ability to move towards the minus-end of the … WebA dynein light chain of sea urchin sperm flagella is a homolog of mouse Tctex 1, which is encoded by a gene of the t complex sterility locus [1]. The chromosomal location and pattern of expression of tctex-1 make it a candidate for involvement in male sterility [2]. Expression of tctex-1 mRNA and protein was observed in all lymphoma lines ... cleaners industrial