WebFactor H (FH) is the main regulator of the complement AP and of its amplification loop in plasma and on cell surface. FH consists of 20 modules called complement control proteins (CCPs). The four N-terminal domains (CCPs 1–4) of FH bind the C3b and the C-terminal domains (CCPs 19–20) are able to bind polyanions such as glycosaminoglycans ... WebBackground: Ileal pouch anal anastomosis (IPAA) is the treatment of choice for chronic, medically refractory mucosal ulcerative colitis, indeterminate colitis, familial adenomatous polyposis (FAP), and a select group of patients with Crohn's disease. Aim: : We report outcomes, complications, and quality of life (QOL) in a cohort of 3707 patients treated at …
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