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Hyal2 protein

WebHyal2 made in HeLa cells but have not further character-ized this defect. In summary, the evidence that Hyal2 is a GPI-anchored cell-surface protein in chondrocytes and other cells is over-whelming, and the conclusion of Chow et al. that Hyal2 is an intracellular protein that is not found on the cell surface WebAU EN. Applications Products Services Support Products Services Support

Recombinant Human Hyaluronidase 2/HYAL2 His-tag Protein, CF

WebHYAL2 PROTEIN STRUCTURE ANTIBODIES AND VALIDATION Protein structures PROTEIN STRUCTUREi Predicted Description: Structure prediction from Alphafold project. Structure version 2 # Chains: 1 # Clinical variants: 0 # Population variants: 296 Antigens: Off On Variants: Off Clinical Population Color scheme: Confidence Residue index Chain … WebWhile HYAL1 is a strict lysosomal hyaluronidase and is active when pH ≤ 5.5 (9), HYAL2 is active in a narrow range of pH 5.0 to 5.5 (6) and is attached to cell membrane via GPI … holiday property bond members https://pipermina.com

Anti-HYAL2 Antibodies Invitrogen - Thermo Fisher Scientific

Hyaluronidase-2 is a multifunctional protein, previously thought to only possess acid-active hyaluronan-degrading enzymatic function. In humans it is encoded by the HYAL2 gene. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosami… WebRecombinant Human Hyaluronidase 2/HYAL2 His-tag Protein, CF Summary Learn more about Fluorescent Glycan Labeling and Detection Product Specifications Purity >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. Endotoxin Level <1.0 EU per 1 μg of the protein by the LAL method. Activity http://antibodysystem.com/product/12097.html holiday property bond ltd

Recombinant Human HYAL2 protein (ab152907) Abcam

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Hyal2 protein

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Web12 jan. 2024 · HYAL2, encoding hyaluronidase 2, degrades extracellular hyaluronan, a critical component of the developing heart and palatal shelf matrix. Transfection assays demonstrated that the gene mutations destabilize the molecule, dramatically reducing HYAL2 protein levels. Web30 nov. 2024 · HYAL2 is a cell-surface protein proposed to act as a hyaluronidase enzyme in concert with HYAL1, the other major mammalian hyaluronidase acting in somatic tissues, catalyzing the degradation of the high molecular weight glycosaminoglycan polymer hyaluronan., Hyaluronan, a core constituent of the extracellular matrix, plays key roles in …

Hyal2 protein

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Web9 apr. 2024 · Products &gt; Proteins/Peptides &gt; Human &gt; Partial-length - Product List - Abnova. Innovate through Integrated Solutions Home; Contact Us; English ... WebDown-regulation of HYAL2 is associated with small cell lung cancer and glioma PMID: 12684632. soluble active form expressed and characterized as Jaagsiekte sheep retrovirus receptor PMID: 15596803. In chondrocytes, HYAL-2 appears to be constitutively expressed and not inducibly regulated by catabolic agents.

WebHYAL2 (LuCa-2, LUCA2) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all … http://antibodysystem.com/product/12097.html

Web15 nov. 2002 · Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give … WebOBJECTIVE: Hyaluronidases (HYAL1 and HYAL2) are key enzymes in the degradation of hyaluronan, and their expression has been altered in various cancer types. We previously showed that hyaluronan accumulation in endometrial carcinomas was correlated with decreased mRNA expression of the HYAL genes.

WebPrestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution. Synonym (s): Anti-Hyaluronoglucosaminidase 2, Anti-LUCA2, …

WebCH DE. Anwendungen Produkte Serviceangebote Support Produkte Serviceangebote Support holiday property bond telephone numberWebHyal2 induction was confirmed by using small interfering RNA (siRNA) expressing lentivirus. These in vitro findings correlated in vivo with smokers, where increased Hyal2 immunoreactivity in the epithelium was associated with augmented levels of HA and the appearance of low molecular mass HA species in bronchial secretions. hull grammar school 1959 1964hull grammar school teachers